Genomic & Bioinformatics Analysis Resource (GenBAR)
Genomics & Bioinformatics Analysis Resource (GenBAR)
GenBAR is a Columbia University core facility supported by the Vagelos College of Physicians and Surgeons (VP&S) Office of Research. It is open to all Columbia faculty, research scientists, and students.
For GenBAR questions, please submit a ticket here.
Bioinformatics Team
The GenBAR Bioinformatics team is responsible for processing Next Generation Sequencing data by using standardized best practices pipelines. All exome and genome samples are processed using a consistent alignment and variant calling pipeline.
Services Provided:
Informatics
- Whole Genome Data processing
- Whole Exome Data processing
- Informatics/IT project support
- Long-term storage of whole genome sequencing data*
- Long-term storage of whole exome sequencing data*
- Short-term storage of whole genome sequencing data*
- Short-term storage of whole exome sequencing data*
- Data delivery of Whole Genome sequencing data under a Data Transfer Agreement
- Data delivery of Whole Exome sequencing data under a Data Transfer Agreement
*Note: fees waived for samples designated as Columbia “control” samples.
ATAV (Analysis Tool for Annotated Variants) Database Queries
- Exome-wide association analysis. Perform case-control association studies of rare coding variants from whole exome or whole genome sequencing data of single nucleotide variants by gene- and region-based collapsing analysis. Includes standard sample quality control checks, genetic ancestry estimation, statistical analysis of rare variant enrichments, and a report summarizing the research findings. Analyses can be performed using standard gene-based collapsing methods or ancestry-clustered testing which can be helpful for mixed ancestry cohorts. Additional charges may be applied for projects that require customized computational methods.
- Automated diagnostic report of sample sequencing data (raw ATAV output)
- Data look-up in ATAV
If you have any questions, please contact [email protected].
Any questions about setting up iLab, please contact [email protected].