This lecture in the Columbia Precision Medicine Initiative, Life Science Entrepreneurship seminar series, features a discussion with distinguished panelists Tom Maniatis, PhD, (Director, Columbia Precision Medicine Initiative), Charles Zuker, PhD, (Professor of Biochemistry and Molecular Biophysics, CUMC), and Tony Evnin (Partner, Venrock). The panel, moderated by Tig Conger, MBA (Heritage Partners), cover topics of Basic Biology, Clinical Application and Pre-Clinical Development, and Intellectual Property.