Genomic & Bioinformatics Analysis Resource (GenBAR)

GenBAR is a Columbia University core facility supported by the Vagelos College of Physicians and Surgeons (VP&S) Office of Research. It is open to all Columbia faculty, research scientists, and students. 

Bioinformatics

The GenBAR Bioinformatics team is responsible for processing Next Generation Sequencing data by using standardized best practices pipelines. All exome and genome samples are processed using a consistent alignment and variant calling pipeline.

GenBAR pipeline

Integrate your genomic data to GenBAR’s harmonized pipeline, which includes thousands of samples. 

GenBAR

GenBAR uses Open Specimen to manage genomic data, to capture information about participants and samples. Open Specimen is an open-source, web-based biobanking software used to manage the entire lifecycle of biological samples (biospecimens) for research, tracking them from collection and storage to processing and distribution. 

GenBAR’s genomic data is part of the Columbia Genomics Information Commons, which is available to search and to use by Columbia researchers. 

GenBAR

Get help from GenBAR 

For GenBAR questions, please submit a ticket here or contact [email protected]

Any questions about setting up iLab, please contact [email protected]

Columbia Genomics Consortium Publications

Polygenic Risk and Rare Variants in Endotypes of Idiopathic Pulmonary Fibrosis

https://pubmed.ncbi.nlm.nih.gov/40502585/

Nephrotic syndrome genomic discovery in the Mass General Brigham Biobank identifies monoallelic MEFV variants as a risk factor for focal segmental glomerulosclerosis

https://pubmed.ncbi.nlm.nih.gov/41453490/